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Peptide Storage — Complete Reference

Comprehensive storage conditions for all FDA-approved and major investigational peptides.

CategoryTemperatureExamples
Frozen−20°C to −80°CLong-term API storage
Refrigerated2–8°CMost reconstituted peptides
Room temperature20–25°CSome stable formulations
Controlled room15–30°CUSP definition
Protection LevelRequirement
Light-sensitiveStore in original carton, protect from light
Light-stableNo special light protection required

ParameterUnopenedIn-Use
Temperature2–8°CUp to 30°C
LightOriginal cartonProtect from light
Shelf life (unopened)24 monthsN/A
Shelf life (in-use)N/A56 days (8 weeks)
Do not freezeYesYes
Do not refrigerate (in-use)N/AMay store ≤30°C
Pen disposalAfter 56 days or expiryDiscard
ParameterSpecification
Temperature20–25°C (room temp)
LightOriginal carton
Shelf life36 months
Do not freezeYes
Do not refrigerateYes
MoistureStore dry
ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤30°C
LightOriginal cartonProtect from light
Shelf life (unopened)24 monthsN/A
Shelf life (in-use)N/A21 days (3 weeks)
Do not freezeYesYes
ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤30°C
LightOriginal cartonProtect from light
Shelf life (unopened)30 monthsN/A
Shelf life (in-use)N/A30 days
Do not freezeYesYes
ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤25°C
LightProtect from lightProtect from light
Shelf life (unopened)24 monthsN/A
Shelf life (in-use)N/A30 days
Do not freezeYesYes
ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤25°C
LightOriginal cartonProtect from light
Shelf life (unopened)24 monthsN/A
Do not freezeYesYes
ReconstitutionUse within 24 hoursAdminister immediately
ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤30°C
LightOriginal cartonProtect from light
Shelf life (unopened)24 monthsN/A
Shelf life (in-use)N/A14 days
Do not freezeYesYes

ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤30°C
LightProtect from lightProtect from light
Shelf life (unopened)24 monthsN/A
Shelf life (in-use)N/A28 days
Do not freezeYesYes

InsulinUnopenedIn-UseShelf Life (In-Use)
Lispro (Humalog)2–8°CRoom temp ≤30°C28 days
Aspart (NovoRapid)2–8°CRoom temp ≤30°C28 days
Glulisine (Apidra)2–8°CRoom temp ≤30°C28 days
Faster aspart (Fiasp)2–8°CRoom temp ≤30°C28 days
Technosphere (Afrezza)2–8°CRoom temp ≤25°C10 days (open inhaler)
InsulinUnopenedIn-UseShelf Life (In-Use)
Glargine U-100 (Lantus)2–8°CRoom temp ≤25°C28 days
Glargine U-300 (Toujeo)2–8°CRoom temp ≤30°C42 days
Detemir (Levemir)2–8°CRoom temp ≤30°C42 days
Degludec (Tresiba)2–8°CRoom temp ≤30°C56 days
Icodec (Awiqli)2–8°CRoom temp ≤30°C56 days
InsulinUnopenedIn-UseShelf Life (In-Use)
Humulin R U-5002–8°CRoom temp ≤25°C40 days
Concentrated Lispro2–8°CRoom temp ≤30°C28 days

ParameterSpecification
Unopened2–8°C
In-use2–8°C (after reconstitution)
Shelf life (unopened)24 months
Shelf life (reconstituted)24 hours
Do not freezeYes
LightOriginal carton
ParameterSpecification
Lyophilized−20°C (long-term) or 2–8°C
Reconstituted2–8°C
Shelf life (lyophilized)12–24 months
Shelf life (reconstituted)30 days
Do not freeze (reconstituted)Yes
ParameterSpecification
Lyophilized−20°C (long-term) or 2–8°C
Reconstituted2–8°C
Shelf life (lyophilized)12–24 months
Shelf life (reconstituted)30 days

ParameterSpecification
Temperature2–8°C
LightOriginal carton
Shelf life36 months
Do not freezeYes
Implant storageRefrigerated until administration
ParameterUnopenedIn-Use
Temperature2–8°CRoom temp ≤25°C
LightOriginal cartonProtect from light
Shelf life (unopened)24 monthsN/A
Shelf life (in-use)N/A30 days
Do not freezeYesYes

ParameterSC VialsLAR Vials
Temperature2–8°C2–8°C
LightProtect from lightProtect from light
Shelf life24 months24 months
ReconstitutedUse within 24 hUse within 24 h
Do not freezeYesYes
ParameterSpecification
Temperature2–8°C
LightOriginal carton
Shelf life36 months
Do not freezeYes
AdministrationRoom temp 30 min before injection
ParameterSCLAR
Temperature2–8°C2–8°C
LightProtect from lightProtect from light
Shelf life24 months24 months
ReconstitutedUse within 24 hUse within 24 h
Do not freezeYesYes

ParameterSpecification
Lyophilized−20°C (long-term) or 2–8°C
Reconstituted2–8°C
Shelf life (lyophilized)12–24 months
Shelf life (reconstituted)30 days
SolventBacteriostatic water or saline
Do not freeze (reconstituted)Yes
ParameterSpecification
Lyophilized−20°C (long-term) or 2–8°C
Reconstituted2–8°C
Shelf life (lyophilized)12–24 months
Shelf life (reconstituted)30 days
SolventBacteriostatic water or saline
Do not freeze (reconstituted)Yes
ParameterSpecification
Powder2–8°C or room temp
Reconstituted2–8°C
Shelf life (powder)24–36 months
Shelf life (reconstituted)30 days
SolventBacteriostatic water or saline

SolventUseStorageShelf Life
Bacteriostatic water (0.9% BA)Most peptidesRoom temp28 days after opening
Sterile water for injectionSensitive peptidesRoom temp24 hours after opening
Normal saline (0.9% NaCl)IM/SC injectionRoom temp24 hours
0.9% BA in NSPeptides requiring BARoom temp28 days
  1. Always check expiry dates before use
  2. Reconstituted peptides are typically stable for 30 days at 2–8°C
  3. Do not freeze reconstituted peptides (protein denaturation risk)
  4. Protect from light unless specified as light-stable
  5. Do not use if solution is discolored, cloudy, or contains particles
  6. In-use storage differs from unopened storage — follow label
  7. Travel: Use insulated cooler with ice packs for <8 hours
  8. Power outage: Keep refrigerated items cold with ice; if >24 hours without cold chain, discard reconstituted peptides
  9. Multi-dose vials contain preservative; single-dose vials do not
  10. Lyophilized peptides are more stable than reconstituted — store lyophilized when possible