Peptide Storage Conditions
Peptide Storage Conditions
Section titled “Peptide Storage Conditions”Lyophilized Peptides
Section titled “Lyophilized Peptides”| Condition | Duration | Temperature | Notes |
|---|---|---|---|
| Short-term | <1 month | 2-8°C | Refrigerated, protect from light |
| Long-term | 1-2 years | -20°C | Frozen, desiccant required |
| Ultra-long | >2 years | -80°C | Flash-freeze, inert atmosphere |
Reconstituted Peptides
Section titled “Reconstituted Peptides”| Condition | Duration | Temperature | Notes |
|---|---|---|---|
| Working solution | <24 hours | 2-8°C | Use within day |
| Short-term | 1-2 weeks | 2-8°C | BAC water required |
| Extended | 2-4 weeks | 2-8°C | Some peptides only |
| Frozen aliquots | 3-6 months | -20°C | Single-use aliquots |
Stability by Peptide Class
Section titled “Stability by Peptide Class”| Class | Lyophilized Stability | Reconstituted Stability | Key Concerns |
|---|---|---|---|
| GLP-1 agonists | >2 years -20°C | 2-4 weeks 2-8°C | Aggregation, deamidation |
| Insulins | >2 years -20°C | 28 days 2-8°C | Fibrillation, potency loss |
| Oxytocin | >1 year -20°C | 1-2 weeks 2-8°C | Cyclicization, oxidation |
| BPC-157 | >2 years -20°C | 4+ weeks 2-8°C | Highly stable |
| GHK-Cu | >2 years -20°C | 4+ weeks 2-8°C | Copper oxidation |
Best Practices
Section titled “Best Practices”- Never freeze reconstituted peptides (ice crystals damage structure)
- Use BAC water (preservative prevents microbial growth)
- Aliquot before freezing (avoid freeze-thaw cycles)
- Protect from light (photodegradation of aromatic residues)
- Track expiry dates (label vials with date and concentration)